Diagnosis, surgery and systemic treatment of brain metastases
نویسندگان
چکیده
منابع مشابه
Systemic treatment of non-small cell lung cancer brain metastases
In the systemic treatment of brain metastases from non-small cell lung cancer (BMF-NSCLC) chemo- and targeted therapy are used. Response rates after platinum-based chemotherapy, range from 23% to 45%. Development of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs): gefitinib or erlotinib, was an improvement in treatment of advanced NSCLC patients. EGFR mutations are prese...
متن کاملSurgery for brain metastases
The use of surgery in the treatment of brain metastases is controversial. Patients who present certain clinical characteristics may experience prolonged survival with resection compared with radiation therapy. Thus, for patients with a single metastatic lesion in the setting of well-controlled systemic cancer, surgery is highly indicated. Stereotactic radiosurgery (SRS) alone can provide a simi...
متن کاملTreatment of Brain Metastases.
Brain metastases (BMs) occur in 10% to 20% of adult patients with cancer, and with increased surveillance and improved systemic control, the incidence is likely to grow. Despite multimodal treatment, prognosis remains poor. Current evidence supports use of whole-brain radiation therapy when patients present with multiple BMs. However, its associated cognitive impairment is a major deterrent in ...
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ژورنال
عنوان ژورنال: Onkologie
سال: 2019
ISSN: 1802-4475,1803-5345
DOI: 10.36290/xon.2019.024